Tweetorial: Long COVID in Children and Adolescents

The content for this activity is available here on Twitter


Long COVID symptoms are both physical and mental in nature among children and adolescents and have the potential to affect long-term functioning and increase the overall burden on health care delivery.

Learning Objective

After completing this educational activity, you should be able to:

  • Monitor children and adolescents for symptoms of long COVID using multidisciplinary approaches

Target Audience

Primary Care Providers

Program Description

Although long SARS-CoV-2 infection is formally recognized as a disability by the U.S. government, familiarity with the condition remains suboptimal in routine clinical practice. Once thought to only affect adults, long SARS-CoV-2 infections appear to be a substantial, mounting source of morbidity among infants, children, and adolescents. Diverse, non-specific neurological sequelae, such as headaches, inattentiveness, and difficulties processing information, complicate efforts to make timely diagnoses, and differentiating between these symptoms and those associated with active infections can prove difficult. Closing existing gaps in recognition and treatment are imperative, as many of the neurologic complications of SARS-CoV-2 and multisystem inflammatory syndrome are life-threatening. Through this educational initiative, participants can enhance their ability to recognize long SARS-CoV-2 infection in pediatric populations and intervene appropriately. In doing so, clinicians can minimize the healthcare burden posed by long SARS-CoV-2 infections and optimize patient-related quality of life.

Additional Information

Activity summary
Available credit: 
  • 0.25 AMA PRA Category 1 Credit™
  • 0.25 Participation
Activity opens: 
Activity expires: 

Support Statement

Supported by Physicians Postgraduate Press, Inc.

Learning Objective

After completing this educational activity, you should be able to:

  • Monitor children and adolescents for symptoms of long COVID using multidisciplinary approaches

Release, Review, and Expiration Dates

This CME activity was published in October 2022 and is eligible for AMA PRA Category 1 Credit™ through October 31, 2023. 

Statement of Need and Purpose

Neuropsychiatric manifestations following SARS-CoV-2 infection are widely accepted in adults, and emerging evidence supports their presence in children and adolescents. That said, findings from recent studies indicate that clinicians are challenged when trying to differentiate between acute and long-term symptoms caused by SARS-CoV-2 infection. Consequently, practitioners need education about the signs and symptoms seen in children and adolescents so that they can be mitigated as early as possible, thereby improving patient outcomes. Additional education is needed on the role of clinical monitoring, multidisciplinary management of physical problems, reasonable academic accommodations, preventive vaccinations, and mental health support. By addressing the complications associated with SARS-CoV-2 in a timely manner, clinicians can substantially improve patient-related quality of life and limit the impact of this emerging chronic condition on healthcare systems nationwide. 

Unlabeled and Investigational Usage

The faculty of this educational activity may include discussions of products or devices that are not currently labeled for use by the FDA. Faculty members have been advised to disclose to the audience any reference to an unlabeled or investigational use.

No endorsement of unapproved products or uses is made or implied by coverage of these products or uses.

Please refer to the official prescribing information for each product for discussion of approved indicators, contraindications and warnings.

Review Process

The faculty members agreed to provide a balanced and evidence-based presentation and discussed the topics and CME objectives during the planning sessions. The faculty’s submitted content was validated by CME Institute staff, and the activity was evaluated for accuracy, use of evidence, and fair balance by the Chair and a peer reviewer who is without conflict of interest.

The opinions expressed herein are those of the faculty and do not necessarily reflect the opinions of the CME provider and publisher or the commercial supporter

© Copyright 2022 Physicians Postgraduate Press, Inc.

Faculty Affiliation

Mayank Gupta, MD 
Clarion Psychiatric Center, Clarion, Pennsylvania 

Nihit Gupta, MD
Reynolds Memorial Hospital, Glendale, West Virginia

Michael Esang, MD 
Clarion Psychiatric Center, Clarion, Pennsylvania 

Financial Disclosure

The CME Institute adheres to the Standards for Integrity and Independence in Accredited Continuing Education of the Accreditation Council for Continuing Medical Education (ACCME). Any individuals in a position to control the content of a continuing education activity, including faculty, content developers, reviewers, staff, and others, are required to disclose to learners the presence or absence of any relevant financial relationships with an ACCME-defined ineligible company within the preceding 24 months of the activity. The ACCME defines an “ineligible company” as one whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

The CME Institute has mitigated all relevant conflicts of interest prior to the commencement of the activity. None of the individuals involved in the content have relevant financial relationships with ineligible companies except the following:  

Relevant financial relationships: 
Drs M. Gupta, N. Gupta, and Esang have no personal affiliations or financial relationships with any commercial interest to disclose relative to this article.

Michael R. Page, PharmD, RPh
Independent Medical Director/Medical Writer
Plainsboro, New Jersey
Dr. Page is a consultant for BioCentric, Inc. and American Medical Communications, Inc.

Lucy Horton, MD, MPH
Independent Peer Reviewer
San Diego, California
Dr. Horton previously received honoraria for speaking/teaching with GSK and previously served on the advisory board with Gilead and GSK.

Accreditation Statement

The CME Institute of Physicians Postgraduate Press, Inc., is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Credit Designation

The CME Institute of Physicians Postgraduate Press, Inc., designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Note: The American Nurses Credentialing Center (ANCC) and the American Academy of Physician Assistants (AAPA) accept certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.

To obtain credit for this activity, study the material and complete the CME Posttest and Evaluation.

Available Credit

  • 0.25 AMA PRA Category 1 Credit™
  • 0.25 Participation


Please login or register to take this activity.

Register for free on our site to participate in this and many other free CME courses.

The content for this activity is available here on Twitter